Tuesday, November 24, 2015

Uncertainty in measured microcystin concentrations using ELISA

We published a paper on the uncertainty in the measured microcystin concentration using the commonly used method known as ELISA.  Microcystin is a group of toxin associated with blooms of cyanobacteria.  One high concentration value detected in a drinking water sample in Toledo in 2014 resulted in a "do not drink" advisor that affected about half a million people in the Toledo area.  In the paper we discussed the high level of uncertainty associated with the estimated concentrations and provided a Bayesian Hierarchical Modeling (BHM) approach for reducing the uncertainty.  I have uploaded data used in that paper to GitHub.

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